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Dr. Edward Basgall

Profile

Extensive multidisciplinary analytical microscopy research and service laboratory experience with FESEM, SEM, EDS, EBSD, ESEM, cryo-SEM, FIB/SEM, Cryo/FIB/SEM, and biological TEM, fluorescence, confocal-laser, brightfield, darkfield and DIC(Nomarski) microscopy.   

Education

  • Ph.D., University of Illinois, Nutritional Sciences, Dept. of Food Science, 1983
  •   B.S., University of Illinois, Microbiology-Chemistry/Physics, Dept of Liberal Arts and Sciences,Jan 1977 1975

Professional Experience

Nov 2007-Present:      SEM Microscopy Manager, Central Research Facility, Drexel University, Philadelphia, PA 19104


Nov 2006-Mar 2007:    Applications Specialist, Carl ZeissSMT, Inc. @ Zeiss Center of Excellence, Univ. of Calif., Irvine, CA 92697


Feb 1998-Jun 2006:    Research Associate-EBeam Lithographer/Nanofabrication Engineer, Penn State Univ. University Park, PA 16802


May 1995-Feb 1998:   Research Associate, Dept. of Chemistry, Penn State Univ., University Park, PA 16802


May 1993-May 1995:  Electron Microscopy Facility Director, Cell Biology and Anatomy Dept., School of Medicine, 
                                 
Medical College of Georgia, Augusta, GA 30912

 

Sept 1989-May 1995:  Senior Microscopist, Advanced Microscopy Facility, Microbiology Dept., UMASS, Amherst, MA 01002


Jan 1984-Sept 1998:   EM Lab Director/Research Associate, Dept of Veterinary Biosciences, Dept of Veterinary Pathobiology,
                                 
Vet.Med. Electron Microscopy Facility, Univ. of Ill., Urbana, IL 16801       

 

Jan 1977-Jun 1981:    Teaching Assistant/Visiting Lecturer, Center for Electron Microscopy, Univ. of Ill. Urbana, IL 16801


Aug 1975-Oct 1983:   Research Assistant, Burnsides Research Lab, Dept of Food Science, Univ. of Ill., Urbana, IL 16801

 

 Research Experience and Skills

§  Scanning Electron Microscopy (SEM)

§  High resolution FESEM

§  Environmental and Variable Pressure SEM

§  Energy Dispersive X-Ray Microanalysis (EDS)

§  Cryo-SEM

§  EBSD

§  SEM sample prep

§  Biologicals

§  Materials

§  Thin Film Metal evaporation

§  Sputter coating

§  Thermal metal deposition

§  EBeam metal deposition

§  Ultramicrotomy

§  Electron Beam Lithography and Photolithography

§  TEM on Biological materials

§  Reactive Ion Etching, Wet Etching and associated fabrication techniques


Courses Taught

§  Introduction to Nanocharacterization (SEM, EDS and sample prep)-Drexel University

§  Transmission Electron Microscopy for biological applications-Lab and Lectures-Univ. of Illinois.

§  Scanning Electron Microscopy for biological applications-Lab and Lectures-Univ. of Illinois


Awards and Recognitions

§  2010 - President's Award Nominee-Drexel University


Activities

  §  Member of the Microscopy Society of America

  §  Member of Philadelphia Society for Microscopy
 §  Member of the American Chemical Society 


Publications

Chang,H., Kosari,F., Andreadakis,G., Vasmatzis,G., Basgall,E., King,A.H., and Bashir,R. Fabrication of a Solid-State Single Nanopore for DNA characterization. Electr.Matls. Conf. Proc. June 2004.

Dwight,D.W.1, LeGault,D.I.1, Allara,D.L.1, Swanson,D.C.2,Lysak,D.B.2, Merdes,D.W.2, Basgall,E.J.3, 1Chemistry Department, 2Applied Research Laboratory and 3Nanofab Center, Penn State University, State College, PA, and Stewart,S. and Treado,P.J., ChemImage Corp., Pittsburgh, PA NDIA Homeland Security Symposium, Arlington, VA, May 25-28, 2004.

Basgall, E.J. Low Voltage FESEM evaluation of nano and microfabricated materials. (Abstract) 60th MSA Proceedings, Quebec City, Quebec, Canada, 2002 Ann Meeting. Microsc.Microanal. 8 (Suppl.2) 1132CD. (poster presentation)

Basgall, E.J. and Winograd, N. Uncoated LVSEM and Imaging TOF-SIMS of unfixed, Plunge Frozen, Freeze Dried, Fungal and Plant Materials.  (Abstract) 50th MSA Proceedings, pp850-851, Atlanta, GA, 1998 Ann. Meeting.

Tompkins, M.M. Basgall, E. Zamrini, E. and Hill, W.D. Apoptotic-like changes in Lewy body-associated disorders and normal aging in substantia nigral neurons. Focus on Parkinson’s Disease, 10:78-79, 1998.

Basgall, E.J., Pacholski, M.L., Brummel, C.L. and Winograd, N. Time-of-Flight Mass Spectrometry of Small Bioactive Molecules on Cryo-fixed Cells. (Abstract) Scanning Microscopy 1996 Meeting, May 11-16, Bethesda, MD.

Tompkins, M.M., Basgall, E.J., Zamrini, E. and Hill, W.D. Apoptotic-like changes in Lewy body-associated disorders and normal aging in substantia nigral neurons. Amer. J. Pathology, 150:119-131, 1997.

Basgall, E.J. Acetonitrile as both dehydration and intermediate fluid for SEM evaporative drying of tissue cultured cells. (Abstract) Scanning, 16:IV87, 1994.

Basgall, E.J. and Day, G.A. High pressure freezing and freeze-fracture of starch gels and food emulsions for high resolution TEM (Abstract) 43rd EMSA Proceedings, pp. 68-69. San Jose, CA, 1991 Ann. Meeting.

Gelberg, H.B., Hall, W.F., Woode, G.N., Basgall, E.J., and Scherba, G. Multinucleate enterocytes associated with experimental Group A porcine rotavirus infection.  Vet. Path. 27:453-454, 1990.

Hooser, S.B., Beasley, V.R., Basgall, E.J., Carmichael, W.W., and Haschek, W.M. Ultrastructural changes induced by Microcystin LR in rats. Vet. Path. 27:9-15, 1990.

Basgall, E.J., Scherba, G., and Gelberg, H.B. Diagnostic virology in Veterinary Pathology: Techniques for negative staining. (Abstract) 40th EMSA Proceedings, pp. 366-367. Milwaukee, WI, 1988 Ann. Meeting.

Hooser, S.B., Beasley, V.R., Basgall, E.J., and HAschek, W.M. Sequential ultrastructural hepatic, pulmonary and renal changes due to Microcystis Aeruginosa hepatotoxin in the rat. (Abstract) FASEB Meeting on Tricothecane, Blue-Green Algal and Marine Toxins: Mechanisms, Detection and Therapy. July 25, 1998.

Hooser, S.B., Basgall, E.J., Beasley, V.R., and Hashek, W.M. Sequential ultrastructural hepatic, pulmonary and renal changes due to Microcystis Aeruginosa hepatotoxin in the rat. (Abstract) Society of Toxicology. 1998 Ann. Meeting.

Hooser, S.B., Basgall, E.J., Beasley, V.R., and Haschek, W.M. Sequential ultrastructural hepatic and ultrastructural pulmonary changes due to Microcystis Aeruginosa hepatotoxin (Cyaniginosin LR) in the rat. (Abstract)Great Lakes Electron Microscopy Affiliates. 1987 Biennial Meeting.

Hooser, S.B., Beasley, V.R.,Basgall, E.J., and Haschek, W.M. Ultrastructural alterations due to Microcystis aeruginosa hepatotoxin in rat liver. (Abstract) American College of Veterinary Pathologists. 1987 Ann. Meeting.

Bechtel, P.J., Oh, D.H., Novakofski, J., and Basgall, E.J. Effect of time and temperature on chicken muscle protein degradation: Electrophoresis and electron microscopy. (Abstract) Poultry Sci. Assoc. 1987 Ann. Meeting.

Hashek, W.M., Pang, V.F., Adams, J.A., Basgall, E.J., Buck, W.B., Lambert, R.J., and Beasley, V.R. Acute T-2 mycotoxicosis in Swine: Comparison of inhalation and intravascular routes of exposure on pulmonary ultrastructure. (Abstract) Soc. Of Toxicology. 1987 Ann. Meeting.

Sherba, G., Hajjar, A.M., Pernikoff, D., Sundberg, J.P.,Basgall, E.J., Nerurkar, L., Monzon, M., andReichmann, M.E. Comparison of a cheetah herpesvirus isolate to feline herpes type 1. (Abstract) Amer. Soc. for Virology. 1987 Ann. Meeting.

Everitt, J.I., Basgall, E.J., Hooser, S.B., and Todd, K.S., Jr. Sarcocystis sp. in the striated muscle of domestic cats, Felis catus. Proc. Helminthol. Soc. of Wash. 54(2):279-281, 1987.

Basgall, E.J., Soong, M.M., and Tompkins, W.A.F. Visualization of cytoskeletal elements and associated retroviral antigens by immunogold TEM of detergent extracted cells. Scanning Electron Microsc. IV, pp. 1419-1425, 1986. Biotechnology and Bioapplication of Colloidal Gold Meeting, New Orleans, LA.

Oreskovich, D.C., Bechtel, P.J., McKeith, F.K., Novakofski, J., and Basgall, E.J. The effect of marinade pH on the physical, chemical and structural properties of beef. (Abstract) Food Technology. 1986 Ann. Meeting.

Vimr, E.R. and Basgall, E.J. Development of coliphage KIF Endoneuramidase for detection and selective modification of polysialic acid in neural glycoconjugates. M(Abstract) Fed. Proc. 45:1824, 1986

Sundberg, J.P., Junge, R.E., O’Banion, M.K.,Basgall, E.J., Harrison, Herron, A., and Shivaprasad, H.L. Cloacal papillomas on psittacines.  Amer. J Vet. Res. 47:927-932, 1986.

Wolff, P.A., Meehan, T.P., Basgall, E.J., Allen, G.P., and Sundberg, J.P. Abortion and perinatal foal mortality associated with equine herpesvirus type 1 in a herd of Grevy’s zebra. J. of the Amer. Vet. Med. Assoc. 189(9):1185-1186, 1986.

Zachary, J.F. and Basgall, E.J. Erythrocyte membrane alterations associated with the attachment and replication of Eperythrozoon suis: A light and electron microscopic study. Vet. Path. 22:164-170, 1985.

Basgall, E.J. , Soong, M.M., and Tompkins, W.A.F. Fluorescent and immunoelectron microscopy of detergent extracted cytoskeletal and associated antigens. (Abstract) 43rd EMSA Proceedings. 1985, Louisville, KY, pp. 582-583.

Bechtel, P.J., McKeith, F.K., Martin, S.E.,Basgall, E.J., and Novakofski, J. Properties of frankfurters processed with different levels of sodium bicarbonate. J. Food Protection 48:861-864, 1985

Becthel, P.J., McKeith, F.K., Martin, S.E., Basgall, E.J., and Novakofski, J. Properties of frankfurters processed with different levels of sodium bicarbonate. (Abstract) 18th Meeting. Midwestern Section, American Society of Animal Science. 1985, Chicago, IL.

Basgall, E.J., Bechtel, P.J., and Mckeith, F. An alternative to critical point drying for preparing meat emulsions for scanning electron microscopy. J. Food Microstructure 2:23-26, 1983.

Basgall, E.J. TEM analysis of Wiebel Palade Bodies in homogenized human umbilical vein endothelial cells. (Abstract) 18th Ann. Electron Microscopy Colloquium Proceedings, 1981, Ames, IA, pp. 28-29.

 

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